DLC1

RNA expression — cross-omics
Cross-omicsRNA → PROTEIN-MSPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, DLC1 RNA expression is significantly associated with the protein abundance of many other proteins, with 23,405 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible DLC1-associated proteins across cancer lineages are SORBS3, PRKG1, and RAI14. Each is linked with DLC1 in more than 9 cancer types. Because this analysis shows association rather than direction, both DLC1-to-partner and partner-to-DLC1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, DLC1 versus SORBS3 in UCEC, with a Pearson correlation of 0.41.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (DLC1→partner) and Y-score (partner→DLC1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner proteinX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECSORBS3 →+0.655+0.661<.001<.001310
UCECPRKG1 →+0.947+0.703<.001<.00139
OVRAI14 →+0.436+1.046<.001<.00139
UCECRSU1 →+0.468+0.584<.001<.00139
BRCASSC5D →+0.837+0.897<.001<.00139
UCECCAVIN1 →+0.771+0.578<.001<.00139
Each partner links to its Q-omics profile. Showing the 6 strongest of 23,405 associations by consensus.

DLC1 vs SORBS3 — UCEC

Per-sample scatter of DLC1 vs SORBS3 in UCEC (Pearson r = 0.41).

Explore this scatter interactively →

Exploration