DLAT

Across TCGA cell cohorts, DLAT RNA expression is significantly associated with the go_rna of many other GO terms, with 4,064 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible DLAT-associated GO terms across cancer lineages are Pyruvate decarboxylation to acetyl-CoA, Meiotic sister chromatid cohesion, centromeric, and Meiotic chromosome condensation. Each is linked with DLAT in more than 18 cancer types. Because this analysis shows association rather than direction, both DLAT-to-partner and partner-to-DLAT results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Pyruvate decarboxylation to acetyl-CoA grouped by DLAT-low versus DLAT-high in LIVER.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (DLAT→partner) and Y-score (partner→DLAT) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LIVER	Pyruvate decarboxylation to acetyl-CoA →	+0.186	+1.257	<.001	<.001	3	19
LIVER	Meiotic sister chromatid cohesion, centromeric →	+0.186	+1.181	.008	.001	3	18
KIDNEY	Meiotic chromosome condensation →	+0.162	+0.906	<.001	<.001	3	15
UPPER_AERODIGESTIVE_TRACT	Spindle checkpoint signaling →	+0.117	+0.845	.004	.003	3	14
UPPER_AERODIGESTIVE_TRACT	Protein localization to kinetochore →	+0.182	+1.258	<.001	<.001	3	14
OESOPHAGUS	Asparaginyl-tRNA aminoacylation →	+0.185	+1.113	<.001	<.001	3	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,064 associations by consensus.

Pyruvate decarboxylation to acetyl-CoA by DLAT expression — LIVER

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