DKK2

Across TCGA cell cohorts, DKK2 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,261 significant associations in total. BONE shows the largest number of these associations.

The most reproducible DKK2-associated GO terms across cancer lineages are Apoptotic process involved in luteolysis, Regulation of intracellular protein transport, and Positive regulation of potassium ion import across plasma membrane. Each is linked with DKK2 in more than 6 cancer types. Because this analysis shows association rather than direction, both DKK2-to-partner and partner-to-DKK2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Apoptotic process involved in luteolysis grouped by DKK2-low versus DKK2-high in OVARY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (DKK2→partner) and Y-score (partner→DKK2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	Apoptotic process involved in luteolysis →	+1.124	+1.186	<.001	.008	3	7
BLOOD_Lymphoma	Regulation of intracellular protein transport →	+0.038	+0.687	.004	.007	3	5
BONE	Positive regulation of potassium ion import across plasma membrane →	-0.183	-3.912	<.001	<.001	3	5
BONE	Negative regulation of tubulin deacetylation →	+1.393	+4.044	<.001	<.001	3	4
SKIN	Positive regulation of iron ion transport →	-1.042	-0.534	<.001	<.001	3	4
SKIN	Positive regulation of iron ion transmembrane transport →	-1.042	-0.534	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,261 associations by consensus.

Apoptotic process involved in luteolysis by DKK2 expression — OVARY

Explore this box plot interactively →