DKC1

Across TCGA patient cohorts, DKC1 protein abundance is significantly associated with the RNA expression of many other genes, with 17,986 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible DKC1-associated genes across cancer lineages are CNRIP1, RPL36A, and MINCR. Each is linked with DKC1 in more than 6 cancer types. Because this analysis shows association rather than direction, both DKC1-to-partner and partner-to-DKC1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, DKC1 versus CNRIP1 in BRCA, with a Pearson correlation of -0.41.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DKC1→partner) and Y-score (partner→DKC1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	CNRIP1 →	-0.923	-0.365	<.001	<.001	3	7
COAD	RPL36A →	+0.606	+0.272	<.001	<.001	3	7
LSCC	MINCR →	+0.694	+0.217	<.001	<.001	3	7
OV	PECAM1 →	-0.853	-0.352	<.001	<.001	3	7
BRCA	SNHG4 →	+0.988	+0.255	<.001	<.001	3	7
OV	EIF3E →	+0.629	+0.366	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 17,986 associations by consensus.

DKC1 vs CNRIP1 — BRCA

Explore this scatter interactively →