DIXDC1

Across TCGA patient cohorts, DIXDC1 protein abundance is significantly associated with the RNA expression of many other genes, with 2,895 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible DIXDC1-associated genes across cancer lineages are LAMA1, SPARC, and COL5A2. Each is linked with DIXDC1 in more than 2 cancer types. Because this analysis shows association rather than direction, both DIXDC1-to-partner and partner-to-DIXDC1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, DIXDC1 versus LAMA1 in CCRCC, with a Pearson correlation of 0.49.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DIXDC1→partner) and Y-score (partner→DIXDC1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CCRCC	LAMA1 →	+1.440	+0.389	<.001	.005	3	3
LSCC	SPARC →	+1.186	+0.737	<.001	<.001	3	3
LSCC	COL5A2 →	+1.357	+0.640	<.001	.001	3	3
LSCC	NOX4 →	+1.358	+0.771	<.001	<.001	3	3
GBM	NEGR1 →	+1.082	+0.307	.002	.005	3	3
UCEC	LINC01091 →	+0.999	+0.292	.002	.003	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,895 associations by consensus.

DIXDC1 vs LAMA1 — CCRCC

Explore this scatter interactively →