DIXDC1

Across TCGA cell cohorts, DIXDC1 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,199 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible DIXDC1-associated GO terms across cancer lineages are Transport along microtubule, Protein localization to cilium, and Forebrain ventricular zone progenitor cell division. Each is linked with DIXDC1 in more than 10 cancer types. Because this analysis shows association rather than direction, both DIXDC1-to-partner and partner-to-DIXDC1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Transport along microtubule grouped by DIXDC1-low versus DIXDC1-high in LUNG_NSCLC_LUSC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (DIXDC1→partner) and Y-score (partner→DIXDC1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUSC	Transport along microtubule →	+0.063	+1.522	.001	.001	3	11
PANCREAS	Protein localization to cilium →	+0.058	+1.080	<.001	<.001	3	11
BLOOD_Myeloma	Forebrain ventricular zone progenitor cell division →	+1.392	+2.111	<.001	<.001	3	10
LUNG_NSCLC_LUSC	Intraciliary retrograde transport →	+0.090	+1.224	.005	.008	2	11
SKIN	Regulation of smoothened signaling pathway →	+0.056	+1.355	<.001	<.001	3	10
URINARY_TRACT	Smoothened signaling pathway →	+0.065	+1.366	<.001	.004	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,199 associations by consensus.

Transport along microtubule by DIXDC1 expression — LUNG_NSCLC_LUSC

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