Across TCGA cell cohorts, DISP3 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,986 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible DISP3-associated GO terms across cancer lineages are Positive regulation of double-strand break repair, Constitutive heterochromatin formation, and Positive regulation of double-strand break repair via homologous recombination. Each is linked with DISP3 in more than 9 cancer types. Because this analysis shows association rather than direction, both DISP3-to-partner and partner-to-DISP3 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (DISP3→partner) and Y-score (partner→DISP3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	Positive regulation of double-strand break repair →	+0.081	+1.831	<.001	<.001	3	10
LUNG_SCLC	Constitutive heterochromatin formation →	+0.097	+1.740	.001	.002	3	8
LUNG_SCLC	Positive regulation of double-strand break repair via homologous recombination →	+0.096	+1.569	<.001	<.001	3	8
LUNG_SCLC	Fat cell proliferation →	-0.285	-1.707	.002	<.001	3	7
LUNG_SCLC	Heterochromatin formation →	+0.065	+1.581	.001	.003	3	7
LUNG_SCLC	Regulation of transcription initiation by RNA polymerase II →	+0.060	+1.421	.002	.002	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,986 associations by consensus.

Exploration

DISP3 survival (RNA) · tumor vs normal (RNA) · all DISP3 data types