DISP2

Across TCGA cell cohorts, DISP2 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,942 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible DISP2-associated GO terms across cancer lineages are Neurotrophin TRK receptor signaling pathway, Regulation of myoblast fusion, and Cellular detoxification. Each is linked with DISP2 in more than 5 cancer types. Because this analysis shows association rather than direction, both DISP2-to-partner and partner-to-DISP2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Neurotrophin TRK receptor signaling pathway grouped by DISP2-low versus DISP2-high in SKIN.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (DISP2→partner) and Y-score (partner→DISP2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	Neurotrophin TRK receptor signaling pathway →	-0.098	-0.665	.001	.001	3	6
STOMACH	Regulation of myoblast fusion →	+0.069	+0.806	.008	.002	3	5
LIVER	Cellular detoxification →	-0.181	-1.420	<.001	<.001	3	5
LIVER	Cellular response to toxic substance →	-0.167	-1.300	<.001	<.001	3	5
STOMACH	Regulation of syncytium formation by plasma membrane fusion →	+0.068	+0.773	.008	.003	3	5
SKIN	Phosphatidylcholine acyl-chain remodeling →	+0.059	+0.495	.003	.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,942 associations by consensus.

Neurotrophin TRK receptor signaling pathway by DISP2 expression — SKIN

Explore this box plot interactively →