DISP1

Across TCGA pan-cancer cohorts, DISP1 mass-spec protein is linked to patient survival in 4 of 34 cancer types, making it a survival-associated DISP1 data layer compared with 20 for mass-spec protein and 7 for mutation status.

The strongest signal is observed in lung adenocarcinoma (LUAD), where higher DISP1 mass-spec protein is associated with worse disease-free survival. In most high-consensus cancer types, elevated DISP1 expression acts as an unfavorable survival marker, although some lineages such as PDAC show a favorable association.

LUAD, PDAC, and UCEC are the cancer types where DISP1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LUAD	DFS	Quartile	II,III,IV	0.797	1.000	.003	8	view →
PDAC	OS	Tertile	All	0.999	0.541	.038	6	view →
UCEC	DFS	Median	II,III,IV	0.513	0.917	.035	4	view →
LSCC	DFS	Tertile	All	0.636	0.854	.049	1	view →

Pink = unfavorable, green = favorable. Showing the 4 strongest of 4 lineages.

DISP1–LUAD (DFS)

Open the LUAD breakdown →