DISP1

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, DISP1 protein abundance is significantly associated with the RNA expression of many other genes, with 4,963 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible DISP1-associated genes across cancer lineages are LINC00886, SSTR1, and INTS3. Each is linked with DISP1 in more than 2 cancer types. Because this analysis shows association rather than direction, both DISP1-to-partner and partner-to-DISP1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, DISP1 versus LINC00886 in PDAC, with a Pearson correlation of 0.72.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DISP1→partner) and Y-score (partner→DISP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
PDACLINC00886 →+0.827+0.782.001.00233
LUADSSTR1 →+0.528+0.633.005<.00133
PDACINTS3 →+0.662+0.797.001.00232
LUADSERTAD4-AS1 →+0.731+0.797.001<.00132
PDACMACROD2-IT1 →+0.982+0.795.005.00232
PDACRAB1C →+0.403+1.086.005<.00132
Each partner links to its Q-omics profile. Showing the 6 strongest of 4,963 associations by consensus.

DISP1 vs LINC00886 — PDAC

Per-sample scatter of DISP1 vs LINC00886 in PDAC (Pearson r = 0.72).

Explore this scatter interactively →

Exploration