DISP1

Across TCGA patient cohorts, DISP1 mutation is significantly associated with the RNA expression of many other genes, with 6,082 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible DISP1-associated genes across cancer lineages are RPL23AP82, PSMD9, and E2F7. Each is linked with DISP1 in more than 3 cancer types. Because this analysis shows association rather than direction, both DISP1-to-partner and partner-to-DISP1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RPL23AP82 grouped by DISP1-low versus DISP1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DISP1→partner) and Y-score (partner→DISP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RPL23AP82 →	+0.392	+1.558	<.001	<.001	3	4
COAD	PSMD9 →	+0.316	+2.375	<.001	.003	3	4
STAD	E2F7 →	+0.672	+2.700	.005	.006	3	4
STAD	PGAM1 →	+0.636	+3.807	<.001	<.001	3	4
UCEC	RRM2 →	+0.654	+2.021	<.001	<.001	3	4
UCEC	LINC00324 →	+0.359	+2.154	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,082 associations by consensus.

RPL23AP82 by DISP1 expression — UCEC

Explore this box plot interactively →