DISP1

Across TCGA cell cohorts, DISP1 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,372 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible DISP1-associated GO terms across cancer lineages are Macroautophagy, Autophagosome assembly, and Positive regulation of organelle assembly. Each is linked with DISP1 in more than 11 cancer types. Because this analysis shows association rather than direction, both DISP1-to-partner and partner-to-DISP1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Macroautophagy grouped by DISP1-low versus DISP1-high in PANCREAS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (DISP1→partner) and Y-score (partner→DISP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PANCREAS	Macroautophagy →	+0.051	+0.437	<.001	.002	3	11
LIVER	Autophagosome assembly →	+0.047	+0.816	.002	.001	2	12
STOMACH	Positive regulation of organelle assembly →	+0.049	+0.769	.008	.003	2	12
PANCREAS	Autophagosome organization →	+0.053	+0.442	.007	.004	2	11
PANCREAS	Vesicle budding from membrane →	+0.085	+0.567	<.001	<.001	3	10
BREAST	Transport along microtubule →	+0.036	+0.516	.001	.002	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,372 associations by consensus.

Macroautophagy by DISP1 expression — PANCREAS

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