DISC1FP1

Across TCGA pan-cancer cohorts, DISC1FP1 RNA is linked to patient survival in 20 of 34 cancer types, making it the most broadly survival-associated DISC1FP1 data layer.

The strongest signal is observed in kidney renal papillary cell carcinoma (KIRP), where higher DISC1FP1 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated DISC1FP1 expression acts as an unfavorable survival marker, although some lineages such as ESCA and READ show a favorable association.

KIRP, MESO, and UVM are the cancer types where DISC1FP1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRP	DFS	Tertile	IV	0.162	0.546	.009	86	view →
MESO	OS	Median	All	0.291	0.477	.004	72	view →
UVM	DFS	Quartile	All	0.536	0.856	<.001	65	view →
ESCA	OS	Median	III,IV	0.730	0.415	.001	63	view →
READ	OS	Median	All	0.777	0.533	<.001	54	view →
COAD	DFS	Quartile	II,III,IV	0.214	0.532	.004	29	view →
LUSC	DFS	Median	II,III,IV	0.867	0.608	.004	22	view →
KICH	OS	Quartile	III,IV	0.612	0.960	.010	14	view →
PAAD	DFS	Median	III,IV	0.370	0.853	.010	12	view →
LAML	DFS	Median	All	0.492	0.643	.015	12	view →
SARC	OS	Quartile	All	0.349	0.643	.016	6	view →
UCEC	DFS	Quartile	IV	0.454	0.777	.031	6	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 20 lineages.

DISC1FP1–KIRP (DFS)

Open the KIRP breakdown →