Across TCGA patient cohorts, DISC1-IT1 RNA expression is significantly associated with the RNA expression of many other genes, with 12,952 significant associations in total. UVM shows the largest number of these associations.

The most reproducible DISC1-IT1-associated genes across cancer lineages are DISC1, RN7SL481P, and ARID4B. Each is linked with DISC1-IT1 in more than 25 cancer types. Because this analysis shows association rather than direction, both DISC1-IT1-to-partner and partner-to-DISC1-IT1 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DISC1-IT1→partner) and Y-score (partner→DISC1-IT1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
MESO	DISC1 →	+0.979	+0.559	<.001	<.001	3	26
LAML	RN7SL481P →	+0.746	+0.732	.001	<.001	3	21
UVM	ARID4B →	+1.197	+0.289	<.001	<.001	3	21
UVM	MATR3 →	+0.761	+0.258	<.001	<.001	3	21
LAML	LRRC37A15P →	+0.626	+0.692	<.001	<.001	3	20
LAML	LINC01572 →	+0.633	+0.839	<.001	<.001	3	20

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,952 associations by consensus.

Exploration

DISC1-IT1 survival (RNA) · tumor vs normal (RNA) · all DISC1-IT1 data types