DISC1-IT1

RNA expression — cross-omics
Cross-omicsRNA → PROTEIN-MSPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, DISC1-IT1 RNA expression is significantly associated with the protein abundance of many other proteins, with 7,526 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible DISC1-IT1-associated proteins across cancer lineages are DISC1_S97, HDGFL3, and POLDIP2. Each is linked with DISC1-IT1 in more than 4 cancer types. Because this analysis shows association rather than direction, both DISC1-IT1-to-partner and partner-to-DISC1-IT1 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (DISC1-IT1→partner) and Y-score (partner→DISC1-IT1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner proteinX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LSCCDISC1_S97 →+0.792+0.815<.001<.00135
HNSCHDGFL3 →+0.534+0.949<.001.00234
CCRCCPOLDIP2 →-0.240-0.583<.001<.00133
CCRCCSORBS3_S373 →+0.597+0.370<.001.00133
LSCCSRP68 →-0.220-0.653<.001<.00133
CCRCCC19orf33_S78 →-1.059-0.457.004.00633
Each partner links to its Q-omics profile. Showing the 6 strongest of 7,526 associations by consensus.

Exploration