Across TCGA pan-cancer cohorts, DIS3L2P1 RNA is linked to patient survival in 19 of 34 cancer types, making it the most broadly survival-associated DIS3L2P1 data layer.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where higher DIS3L2P1 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated DIS3L2P1 expression acts as an unfavorable survival marker, although some lineages such as UCEC show a favorable association.

KIRC, READ, and KICH are the cancer types where DIS3L2P1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRC	OS	Tertile	All	0.659	0.818	<.001	150	view →
READ	OS	Tertile	III,IV	0.330	0.900	<.001	72	view →
KICH	DFS	Tertile	All	0.521	0.971	<.001	54	view →
UCEC	DFS	Median	All	0.758	0.563	.002	52	view →
BRCA	OS	Tertile	IV	0.233	0.755	.038	36	view →
UCS	DFS	Tertile	IV	0.132	0.718	.002	36	view →
UVM	DFS	Tertile	All	0.203	0.773	.003	36	view →
MESO	DFS	Tertile	II,III,IV	0.099	0.406	.034	27	view →
DLBC	OS	Tertile	III,IV	0.175	0.874	.025	27	view →
THCA	OS	Tertile	II,III,IV	0.862	0.957	.017	18	view →
LUAD	DFS	Tertile	IV	0.333	0.671	.048	18	view →
TGCT	OS	Tertile	III,IV	0.501	1.000	.014	18	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 19 lineages.

Exploration

Same gene, other analysis: DIS3L2P1 tumor-vs-normal RNA expression · all DIS3L2P1 data types