DIS3L2

Across TCGA patient cohorts, DIS3L2 protein abundance is significantly associated with the RNA expression of many other genes, with 3,953 significant associations in total. GBM shows the largest number of these associations.

The most reproducible DIS3L2-associated genes across cancer lineages are NDUFA10, FBXO36, and PSMD1. Each is linked with DIS3L2 in more than 6 cancer types. Because this analysis shows association rather than direction, both DIS3L2-to-partner and partner-to-DIS3L2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, DIS3L2 versus NDUFA10 in OV, with a Pearson correlation of 0.45.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DIS3L2→partner) and Y-score (partner→DIS3L2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	NDUFA10 →	+0.603	+0.399	<.001	<.001	3	7
HNSC	FBXO36 →	+0.651	+0.173	<.001	.001	3	7
LUAD	PSMD1 →	+0.400	+0.168	<.001	<.001	3	6
OV	USP40 →	+0.968	+0.392	<.001	<.001	3	6
CCRCC	MRPL44 →	+0.512	+0.208	<.001	<.001	3	5
OV	UBE2F →	+0.550	+0.413	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,953 associations by consensus.

DIS3L2 vs NDUFA10 — OV

Explore this scatter interactively →