DIRAS1

Across TCGA patient cohorts, DIRAS1 RNA expression is significantly associated with the protein abundance of many other proteins, with 17,693 significant associations in total. GBM shows the largest number of these associations.

The most reproducible DIRAS1-associated proteins across cancer lineages are DNM1, PALLD, and RAB23. Each is linked with DIRAS1 in more than 6 cancer types. Because this analysis shows association rather than direction, both DIRAS1-to-partner and partner-to-DIRAS1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, DIRAS1 versus DNM1 in OV, with a Pearson correlation of 0.44.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (DIRAS1→partner) and Y-score (partner→DIRAS1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	DNM1 →	+0.516	+0.896	<.001	<.001	3	7
OV	PALLD →	+0.784	+0.755	<.001	<.001	3	6
CCRCC	RAB23 →	+0.518	+0.210	<.001	<.001	3	6
OV	SNX18 →	+0.694	+1.039	<.001	<.001	3	6
OV	ASPN →	+1.024	+0.711	<.001	<.001	3	6
UCEC	PALM_S116 →	+0.773	+0.646	.001	.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 17,693 associations by consensus.

DIRAS1 vs DNM1 — OV

Explore this scatter interactively →