DIPK2B

Across TCGA patient cohorts, DIPK2B mutation is significantly associated with the total protein of many other genes, with 32 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible DIPK2B-associated genes across cancer lineages are A-Raf_pS299, FoxM1, and Gab2. Each is linked with DIPK2B in more than 1 cancer types. Because this analysis shows association rather than direction, both DIPK2B-to-partner and partner-to-DIPK2B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, A-Raf_pS299 grouped by DIPK2B-low versus DIPK2B-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DIPK2B→partner) and Y-score (partner→DIPK2B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	A-Raf_pS299 →	-0.116	-1.502	.003	.027	3	1
UCEC	FoxM1 →	+0.194	+1.392	.023	.019	3	1
UCEC	Gab2 →	+0.239	+2.321	.042	.033	3	1
UCEC	JNK_pT183_Y185 →	-0.133	-1.678	.016	.021	3	1
UCEC	JNK2 →	+0.205	+1.938	.001	.001	3	1
UCEC	Ku80 →	+0.213	+1.665	.006	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 32 associations by consensus.

A-Raf_pS299 by DIPK2B expression — UCEC

Explore this box plot interactively →