DIPK2B

Across TCGA cell cohorts, DIPK2B mutation is significantly associated with the RNA expression of many other genes, with 6 significant associations in total. LUNG_NSCLC_LUAD shows the largest number of these associations.

The most reproducible DIPK2B-associated genes across cancer lineages are LRRC74A, HIGD1C, and MAGEB4. Each is linked with DIPK2B in more than 1 cancer types. Because this analysis shows association rather than direction, both DIPK2B-to-partner and partner-to-DIPK2B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, LRRC74A grouped by DIPK2B-low versus DIPK2B-high in LUNG_NSCLC_LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DIPK2B→partner) and Y-score (partner→DIPK2B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	LRRC74A →	+0.012	+5.266	<.001	.001	3	1
LUNG_NSCLC_LUAD	HIGD1C →	+0.065	+4.662	<.001	.005	3	1
LARGE_INTESTINE	MAGEB4 →	+0.012	+5.415	.009	.004	3	1
LARGE_INTESTINE	OR10W1 →	+0.022	+4.977	<.001	.007	3	1
SKIN	OR52E4 →	+0.043	+4.273	<.001	.006	3	1
SKIN	NCR2 →	+0.015	+5.022	<.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 6 associations by consensus.

LRRC74A by DIPK2B expression — LUNG_NSCLC_LUAD

Explore this box plot interactively →