DIPK2A

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, DIPK2A protein abundance is significantly associated with the RNA expression of many other genes, with 15,643 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible DIPK2A-associated genes across cancer lineages are OTX1, HJURP, and SIX4. Each is linked with DIPK2A in more than 4 cancer types. Because this analysis shows association rather than direction, both DIPK2A-to-partner and partner-to-DIPK2A results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, DIPK2A versus OTX1 in HNSC, with a Pearson correlation of 0.44.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DIPK2A→partner) and Y-score (partner→DIPK2A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
HNSCOTX1 →+0.856+0.536<.001<.00135
BRCAHJURP →+0.819+0.751.001<.00135
HNSCSIX4 →+0.782+0.561<.001<.00134
UCECPGM5 →-1.208-0.299<.001.00634
LSCCCHAF1B →+0.835+0.755<.001<.00134
BRCAVWA2 →-1.258-0.478.005.00234
Each partner links to its Q-omics profile. Showing the 6 strongest of 15,643 associations by consensus.

DIPK2A vs OTX1 — HNSC

Per-sample scatter of DIPK2A vs OTX1 in HNSC (Pearson r = 0.44).

Explore this scatter interactively →

Exploration