DIPK2A

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, DIPK2A mutation is significantly associated with the RNA expression of many other genes, with 4,624 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible DIPK2A-associated genes across cancer lineages are RNU7-110P, LINC00333, and RN7SL237P. Each is linked with DIPK2A in more than 2 cancer types. Because this analysis shows association rather than direction, both DIPK2A-to-partner and partner-to-DIPK2A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU7-110P grouped by DIPK2A-low versus DIPK2A-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DIPK2A→partner) and Y-score (partner→DIPK2A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
SKCMRNU7-110P →+0.728+4.324<.001.00733
HNSCLINC00333 →+0.407+5.368<.001.00532
BLCARN7SL237P →+0.322+4.973<.001.00932
UCECRAD51AP2 →+0.115+1.783.006<.00132
COADMIR578 →+0.399+4.790<.001.00632
STADRNU4-17P →+0.203+5.070<.001.00432
Each partner links to its Q-omics profile. Showing the 6 strongest of 4,624 associations by consensus.

RNU7-110P by DIPK2A expression — SKCM

Box plot of RNU7-110P in DIPK2A-low vs DIPK2A-high samples in SKCM.

Explore this box plot interactively →

Exploration