DIPK2A

Across TCGA patient cohorts, DIPK2A mutation is significantly associated with the total protein of many other genes, with 33 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible DIPK2A-associated genes across cancer lineages are ASNS, Notch1, and eIF4E. Each is linked with DIPK2A in more than 2 cancer types. Because this analysis shows association rather than direction, both DIPK2A-to-partner and partner-to-DIPK2A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ASNS grouped by DIPK2A-low versus DIPK2A-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DIPK2A→partner) and Y-score (partner→DIPK2A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	ASNS →	+0.368	+1.362	.003	.037	3	3
UCEC	Notch1 →	+0.111	+2.916	.025	<.001	3	2
UCEC	eIF4E →	+0.235	+2.874	.001	<.001	3	1
UCEC	A-Raf_pS299 →	-0.084	-1.584	.046	.034	3	1
UCEC	ERK2 →	+0.149	+3.459	.028	.005	3	1
UCEC	FOXO3a_pS318_S321 →	-0.140	-2.222	.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 33 associations by consensus.

ASNS by DIPK2A expression — UCEC

Explore this box plot interactively →