DIPK2A

Across TCGA cell cohorts, DIPK2A RNA expression is significantly associated with the go_rna of many other GO terms, with 2,614 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible DIPK2A-associated GO terms across cancer lineages are Regulation of protein kinase C activity, Positive regulation of protein kinase C activity, and Cardiac muscle tissue growth. Each is linked with DIPK2A in more than 14 cancer types. Because this analysis shows association rather than direction, both DIPK2A-to-partner and partner-to-DIPK2A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of protein kinase C activity grouped by DIPK2A-low versus DIPK2A-high in LIVER.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (DIPK2A→partner) and Y-score (partner→DIPK2A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LIVER	Regulation of protein kinase C activity →	+1.251	+1.170	.002	.006	2	15
LIVER	Positive regulation of protein kinase C activity →	+1.251	+1.170	.002	.006	2	15
URINARY_TRACT	Cardiac muscle tissue growth →	+0.147	+1.894	.004	<.001	3	13
LUNG_SCLC	Cardiac muscle cell proliferation →	+0.144	+1.973	.006	<.001	2	13
UPPER_AERODIGESTIVE_TRACT	Establishment of mitotic sister chromatid cohesion →	+0.105	+1.094	.006	.009	3	8
URINARY_TRACT	Regulation of endoplasmic reticulum tubular network organization →	+0.066	+1.253	.003	.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,614 associations by consensus.

Regulation of protein kinase C activity by DIPK2A expression — LIVER

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