Across TCGA pan-cancer cohorts, DIPK1C Mutation is linked to patient survival in 3 of 34 cancer types, making it a survival-associated DIPK1C data layer compared with 19 for mass-spec protein.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where higher DIPK1C Mutation is associated with worse disease-free survival. In most high-consensus cancer types, elevated DIPK1C expression acts as an unfavorable survival marker, although some lineages such as UCEC show a favorable association.

HNSC, LIHC, and UCEC are the cancer types where DIPK1C Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
HNSC	DFS	Median	All	0.153	0.697	<.001	39	view →
LIHC	DFS	Median	All	0.044	0.553	<.001	12	view →
UCEC	DFS	Median	All	1.000	0.630	.031	4	view →

Pink = unfavorable, green = favorable. Showing the 3 strongest of 3 lineages.

Exploration

Same gene, other analysis: DIPK1C tumor-vs-normal RNA expression · all DIPK1C data types