DIPK1C

mutation — cross-omics
Cross-omicsMUTATION → PROTEIN-RPPAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, DIPK1C mutation is significantly associated with the total protein of many other genes, with 17 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible DIPK1C-associated genes across cancer lineages are Notch1, ATM, and EGFR_pY1068. Each is linked with DIPK1C in more than 1 cancer types. Because this analysis shows association rather than direction, both DIPK1C-to-partner and partner-to-DIPK1C results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DIPK1C→partner) and Y-score (partner→DIPK1C) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECNotch1 →+0.279+3.472<.001.00232
UCECATM →-0.687-2.000<.001.03232
UCECEGFR_pY1068 →-0.225-2.000.046.03231
UCECPCNA →+0.241+2.000.013.03231
UCECPDCD4 →-0.523-2.000.013.03231
UCECRad50 →-0.247-2.000.023.03231
Each partner links to its Q-omics profile. Showing the 6 strongest of 17 associations by consensus.

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