DIPK1B

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, DIPK1B mutation is significantly associated with the RNA expression of many other genes, with 671 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible DIPK1B-associated genes across cancer lineages are RNU5A-3P, MIR4748, and RNU6-497P. Each is linked with DIPK1B in more than 1 cancer types. Because this analysis shows association rather than direction, both DIPK1B-to-partner and partner-to-DIPK1B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU5A-3P grouped by DIPK1B-low versus DIPK1B-high in LIHC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DIPK1B→partner) and Y-score (partner→DIPK1B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LIHCRNU5A-3P →+0.275+5.033.003.00932
LIHCMIR4748 →+0.387+5.878<.001.00232
LIHCRNU6-497P →+0.306+5.758.006.00332
SKCMGEMIN2P2 →+0.058+3.993<.001.00532
SKCMRRM2P4 →+0.053+5.039<.001.00332
SKCMRNU7-56P →+0.359+4.614<.001.00632
Each partner links to its Q-omics profile. Showing the 6 strongest of 671 associations by consensus.

RNU5A-3P by DIPK1B expression — LIHC

Box plot of RNU5A-3P in DIPK1B-low vs DIPK1B-high samples in LIHC.

Explore this box plot interactively →

Exploration