DIPK1B

Across TCGA cell cohorts, DIPK1B mutation is significantly associated with the RNA expression of many other genes, with 214 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible DIPK1B-associated genes across cancer lineages are CBY1, ARFRP1, and ADNP2. Each is linked with DIPK1B in more than 1 cancer types. Because this analysis shows association rather than direction, both DIPK1B-to-partner and partner-to-DIPK1B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CBY1 grouped by DIPK1B-low versus DIPK1B-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DIPK1B→partner) and Y-score (partner→DIPK1B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	CBY1 →	+0.794	+3.160	<.001	.006	3	1
LARGE_INTESTINE	ARFRP1 →	-0.643	-3.278	.007	.006	3	1
LARGE_INTESTINE	ADNP2 →	+0.826	+3.364	<.001	.002	3	1
LARGE_INTESTINE	RBFA →	+0.705	+3.364	.005	.002	3	1
LARGE_INTESTINE	UBXN8 →	+0.834	+3.169	.001	.009	3	1
LARGE_INTESTINE	TBC1D12 →	+0.936	+3.364	<.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 214 associations by consensus.

CBY1 by DIPK1B expression — LARGE_INTESTINE

Explore this box plot interactively →