DIPK1A

mass-spec protein & survival
Survivalmass-specKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, DIPK1A mass-spec protein is linked to patient survival in 3 of 34 cancer types, making it a survival-associated DIPK1A data layer compared with 25 for mass-spec protein and 1 for mutation status.

The strongest signal is observed in clear cell renal cell carcinoma (CCRCC), where higher DIPK1A mass-spec protein is associated with worse disease-free survival. In most high-consensus cancer types, elevated DIPK1A expression acts as an unfavorable survival marker.

CCRCC, LUAD, and PDAC are the cancer types where DIPK1A mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
CCRCCDFSTertileIII,IV0.2190.819.02411view →
LUADDFSMedianII,III,IV0.7651.000.0227view →
PDACOSMedianIV0.2220.962.0383view →
Pink = unfavorable, green = favorable. Showing the 3 strongest of 3 lineages.

DIPK1A–CCRCC (DFS)

Kaplan–Meier survival curve for DIPK1A mass-spec protein-high vs -low samples in CCRCC.

Open the CCRCC breakdown →

Exploration