DIPK1A

Across TCGA patient cohorts, DIPK1A mutation is significantly associated with the RNA expression of many other genes, with 1,621 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible DIPK1A-associated genes across cancer lineages are RNA5SP412, ESS2, and GGA1. Each is linked with DIPK1A in more than 1 cancer types. Because this analysis shows association rather than direction, both DIPK1A-to-partner and partner-to-DIPK1A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNA5SP412 grouped by DIPK1A-low versus DIPK1A-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DIPK1A→partner) and Y-score (partner→DIPK1A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RNA5SP412 →	+0.501	+2.060	<.001	.002	3	2
UCEC	ESS2 →	+0.278	+1.858	.003	.005	3	1
UCEC	GGA1 →	+0.314	+2.758	.004	<.001	3	1
UCEC	CENPM →	+0.577	+2.736	.003	<.001	3	1
UCEC	JOSD1 →	+0.393	+2.246	.007	.005	3	1
UCEC	SBF1 →	+0.579	+2.269	<.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,621 associations by consensus.

RNA5SP412 by DIPK1A expression — UCEC

Explore this box plot interactively →