DIPK1A

Across TCGA cell cohorts, DIPK1A mutation is significantly associated with the RNA expression of many other genes, with 5 significant associations in total. LUNG_NSCLC_LUAD shows the largest number of these associations.

The most reproducible DIPK1A-associated genes across cancer lineages are OR10W1, KIR2DS4, and KRT28. Each is linked with DIPK1A in more than 1 cancer types. Because this analysis shows association rather than direction, both DIPK1A-to-partner and partner-to-DIPK1A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR10W1 grouped by DIPK1A-low versus DIPK1A-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DIPK1A→partner) and Y-score (partner→DIPK1A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	OR10W1 →	+0.019	+4.562	<.001	<.001	3	1
LARGE_INTESTINE	KIR2DS4 →	+0.009	+3.930	<.001	.003	3	1
LUNG_NSCLC_LUAD	KRT28 →	+0.006	+4.544	<.001	.003	3	1
LUNG_NSCLC_LUAD	URAD →	+0.054	+4.371	<.001	.005	3	1
LUNG_NSCLC_LUAD	TEX33 →	+0.027	+5.266	<.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 5 strongest of 5 associations by consensus.

OR10W1 by DIPK1A expression — LARGE_INTESTINE

Explore this box plot interactively →