DIP2C-AS1

Across TCGA pan-cancer cohorts, DIP2C-AS1 RNA is linked to patient survival in 21 of 34 cancer types, making it the most broadly survival-associated DIP2C-AS1 data layer compared with 5 for mutation status.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where higher DIP2C-AS1 RNA is associated with better overall survival. In most high-consensus cancer types, elevated DIP2C-AS1 expression acts as an unfavorable survival marker, although some lineages such as KIRC and MESO show a favorable association.

KIRC, UVM, and MESO are the cancer types where DIP2C-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRC	OS	Median	All	0.707	0.553	<.001	161	view →
UVM	DFS	Median	All	0.426	0.729	<.001	83	view →
MESO	DFS	Median	All	0.467	0.262	<.001	82	view →
HNSC	OS	Median	IV	0.517	0.291	.002	56	view →
BLCA	DFS	Median	IV	0.121	0.307	.005	40	view →
LGG	DFS	Quartile	All	0.770	0.897	.002	28	view →
LUSC	OS	Quartile	All	0.269	0.513	.001	25	view →
UCS	DFS	Tertile	IV	0.843	0.250	.024	24	view →
ESCA	OS	Tertile	All	0.598	0.777	.019	20	view →
PAAD	DFS	Tertile	All	0.546	0.386	.014	15	view →
KIRP	DFS	Quartile	III,IV	1.000	0.310	.031	12	view →
SKCM	OS	Quartile	All	0.750	0.824	.024	9	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 21 lineages.

DIP2C-AS1–KIRC (OS)

Open the KIRC breakdown →