DIP2B

Across TCGA pan-cancer cohorts, DIP2B mass-spec protein is linked to patient survival in 6 of 34 cancer types, making it a survival-associated DIP2B data layer compared with 26 for mass-spec protein and 7 for mutation status.

The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where higher DIP2B mass-spec protein is associated with better overall survival. In most high-consensus cancer types, elevated DIP2B expression acts as an unfavorable survival marker, although some lineages such as UCEC and HNSC show a favorable association.

UCEC, HNSC, and LUAD are the cancer types where DIP2B mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UCEC	OS	Median	II,III,IV	1.000	0.580	.006	40	view →
HNSC	DFS	Tertile	All	1.000	0.881	.002	33	view →
LUAD	DFS	Quartile	III,IV	0.317	0.768	.016	14	view →
PDAC	DFS	Median	III,IV	0.732	0.321	.003	10	view →
CCRCC	DFS	Median	All	0.615	0.857	.009	6	view →
LSCC	DFS	Median	II,III,IV	0.963	0.868	.046	1	view →

Pink = unfavorable, green = favorable. Showing the 6 strongest of 6 lineages.

DIP2B–UCEC (OS)

Open the UCEC breakdown →