DIP2B

Across TCGA patient cohorts, DIP2B mutation is significantly associated with the RNA expression of many other genes, with 5,913 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible DIP2B-associated genes across cancer lineages are ALDOA, MRPS18C, and GHITM. Each is linked with DIP2B in more than 3 cancer types. Because this analysis shows association rather than direction, both DIP2B-to-partner and partner-to-DIP2B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ALDOA grouped by DIP2B-low versus DIP2B-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DIP2B→partner) and Y-score (partner→DIP2B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	ALDOA →	+0.413	+1.959	<.001	<.001	3	4
COAD	MRPS18C →	+0.341	+3.200	<.001	.009	3	4
UCEC	GHITM →	+0.542	+2.169	<.001	<.001	3	4
COAD	MRM3 →	+0.641	+3.637	<.001	.001	3	4
UCEC	UQCRH →	+0.606	+2.695	.004	<.001	3	4
UCEC	HASPIN →	+1.067	+2.662	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,913 associations by consensus.

ALDOA by DIP2B expression — UCEC

Explore this box plot interactively →