DIP2A

Across TCGA cell cohorts, DIP2A mutation is significantly associated with the RNA expression of many other genes, with 429 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible DIP2A-associated genes across cancer lineages are MMP26, CHSY3, and GAL3ST2. Each is linked with DIP2A in more than 2 cancer types. Because this analysis shows association rather than direction, both DIP2A-to-partner and partner-to-DIP2A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MMP26 grouped by DIP2A-low versus DIP2A-high in STOMACH.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DIP2A→partner) and Y-score (partner→DIP2A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	MMP26 →	+0.505	+4.285	<.001	.007	3	2
LARGE_INTESTINE	CHSY3 →	+0.508	+3.474	<.001	.003	3	2
BLOOD_Leukemia	GAL3ST2 →	+0.215	+3.413	<.001	.004	3	2
BLOOD_Leukemia	NRTN →	+0.722	+3.199	.006	.007	3	2
BLOOD_Leukemia	LRRC20 →	+1.041	+3.199	.005	.007	3	2
BLOOD_Leukemia	DCAKD →	+0.710	+3.215	<.001	.005	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 429 associations by consensus.

MMP26 by DIP2A expression — STOMACH

Explore this box plot interactively →