DIMT1

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, DIMT1 protein abundance is significantly associated with the RNA expression of many other genes, with 13,962 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible DIMT1-associated genes across cancer lineages are NDUFAF2, IRAG1, and CENPH. Each is linked with DIMT1 in more than 5 cancer types. Because this analysis shows association rather than direction, both DIMT1-to-partner and partner-to-DIMT1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, DIMT1 versus NDUFAF2 in OV, with a Pearson correlation of 0.53.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DIMT1→partner) and Y-score (partner→DIMT1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
OVNDUFAF2 →+0.514+0.401<.001<.00136
OVIRAG1 →-0.862-0.315.004.00336
HNSCCENPH →+0.961+0.248<.001<.00136
HNSCPOLR1E →+0.481+0.170.008<.00135
HNSCBTF3 →+0.782+0.228.006.00126
OVSMN1 →+0.694+0.336<.001.00135
Each partner links to its Q-omics profile. Showing the 6 strongest of 13,962 associations by consensus.

DIMT1 vs NDUFAF2 — OV

Per-sample scatter of DIMT1 vs NDUFAF2 in OV (Pearson r = 0.53).

Explore this scatter interactively →

Exploration