DIMT1

Across TCGA patient cohorts, DIMT1 mutation is significantly associated with the RNA expression of many other genes, with 792 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible DIMT1-associated genes across cancer lineages are LINC02707, RNU6-929P, and MIR8082. Each is linked with DIMT1 in more than 1 cancer types. Because this analysis shows association rather than direction, both DIMT1-to-partner and partner-to-DIMT1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, LINC02707 grouped by DIMT1-low versus DIMT1-high in BLCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DIMT1→partner) and Y-score (partner→DIMT1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLCA	LINC02707 →	+0.365	+4.497	<.001	.005	3	2
COAD	RNU6-929P →	+0.368	+7.741	<.001	.009	3	1
BLCA	MIR8082 →	+0.377	+5.618	<.001	.002	3	1
BLCA	MIR6729 →	+0.449	+6.307	<.001	<.001	3	1
BLCA	CPS1-IT1 →	+0.023	+5.444	<.001	.002	3	1
LIHC	MIR500A →	+0.423	+8.503	<.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 792 associations by consensus.

LINC02707 by DIMT1 expression — BLCA

Explore this box plot interactively →