DIMT1

Across TCGA cell cohorts, DIMT1 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,257 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible DIMT1-associated GO terms across cancer lineages are Positive regulation of rRNA processing, Maturation of SSU-rRNA, and rRNA processing. Each is linked with DIMT1 in more than 19 cancer types. Because this analysis shows association rather than direction, both DIMT1-to-partner and partner-to-DIMT1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of rRNA processing grouped by DIMT1-low versus DIMT1-high in OESOPHAGUS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (DIMT1→partner) and Y-score (partner→DIMT1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	Positive regulation of rRNA processing →	+0.140	+0.957	.003	.001	2	20
LUNG_SCLC	Maturation of SSU-rRNA →	+0.137	+0.817	<.001	.002	3	18
LUNG_SCLC	rRNA processing →	+0.127	+0.886	<.001	<.001	3	17
OVARY	Maturation of 5.8S rRNA →	+0.079	+0.836	<.001	<.001	3	16
LUNG_SCLC	rRNA metabolic process →	+0.122	+0.773	<.001	.001	3	16
LUNG_SCLC	Ribosome biogenesis →	+0.107	+0.816	<.001	<.001	2	16

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,257 associations by consensus.

Positive regulation of rRNA processing by DIMT1 expression — OESOPHAGUS

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