DIDO1

Across TCGA patient cohorts, DIDO1 protein abundance is significantly associated with the RNA expression of many other genes, with 24,036 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible DIDO1-associated genes across cancer lineages are TMEM97, CHTOP, and GID8. Each is linked with DIDO1 in more than 7 cancer types. Because this analysis shows association rather than direction, both DIDO1-to-partner and partner-to-DIDO1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, DIDO1 versus TMEM97 in HNSC, with a Pearson correlation of 0.55.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DIDO1→partner) and Y-score (partner→DIDO1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	TMEM97 →	+1.240	+0.351	<.001	<.001	3	8
LSCC	CHTOP →	+0.493	+0.206	<.001	<.001	3	8
LSCC	GID8 →	+0.598	+0.274	<.001	<.001	3	8
HNSC	TADA1 →	+0.622	+0.242	<.001	<.001	3	7
HNSC	TTI1 →	+0.917	+0.345	<.001	<.001	3	7
HNSC	NCOA5 →	+0.749	+0.315	.006	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 24,036 associations by consensus.

DIDO1 vs TMEM97 — HNSC

Explore this scatter interactively →