DIDO1

Across TCGA patient cohorts, DIDO1 protein abundance is significantly associated with the protein abundance of many other proteins, with 40,686 significant associations in total. GBM shows the largest number of these associations.

The most reproducible DIDO1-associated proteins across cancer lineages are AQR, BCLAF1, and ADNP. Each is linked with DIDO1 in more than 9 cancer types. Because this analysis shows association rather than direction, both DIDO1-to-partner and partner-to-DIDO1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, DIDO1 versus AQR in LSCC, with a Pearson correlation of 0.65.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (DIDO1→partner) and Y-score (partner→DIDO1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	AQR →	+0.364	+0.268	<.001	<.001	3	10
GBM	BCLAF1 →	+0.435	+0.379	<.001	<.001	3	10
GBM	ADNP →	+0.529	+0.387	<.001	<.001	3	10
GBM	CPSF6 →	+0.346	+0.372	<.001	<.001	3	10
GBM	DDX17 →	+0.424	+0.417	<.001	<.001	3	10
OV	RTF2 →	+0.455	+0.342	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 40,686 associations by consensus.

DIDO1 vs AQR — LSCC

Explore this scatter interactively →