DIAPH3

Across TCGA patient cohorts, DIAPH3 protein abundance is significantly associated with the RNA expression of many other genes, with 7,143 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible DIAPH3-associated genes across cancer lineages are CEP55, TPX2, and FBXO5. Each is linked with DIAPH3 in more than 5 cancer types. Because this analysis shows association rather than direction, both DIAPH3-to-partner and partner-to-DIAPH3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, DIAPH3 versus CEP55 in UCEC, with a Pearson correlation of 0.67.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DIAPH3→partner) and Y-score (partner→DIAPH3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	CEP55 →	+1.003	+0.527	<.001	<.001	3	6
UCEC	TPX2 →	+1.409	+0.587	<.001	<.001	3	6
UCEC	FBXO5 →	+0.678	+0.541	<.001	<.001	3	5
UCEC	ANLN →	+1.026	+0.515	<.001	<.001	3	5
UCEC	CENPA →	+1.271	+0.615	<.001	<.001	3	5
UCEC	KIF14 →	+0.980	+0.499	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,143 associations by consensus.

DIAPH3 vs CEP55 — UCEC

Explore this scatter interactively →