Across TCGA pan-cancer cohorts, DIAPH3-AS1 RNA differs between tumor and matched normal tissue in 2 of 18 cancer types tested, making tumor–normal expression one of DIAPH3-AS1’s most consistent transcriptional readouts.

The strongest signal is observed in breast invasive carcinoma (BRCA), where DIAPH3-AS1 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types DIAPH3-AS1 is over-expressed in tumor.

BRCA and STAD are the cancer types where DIAPH3-AS1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in DIAPH3-AS1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
BRCA	Female	All	+0.080	.028	2	view →
STAD	All	III,IV	+0.065	.048	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 2 strongest of 2 lineages.

Exploration

Same gene, other analysis: DIAPH3-AS1 RNA expression & survival · all DIAPH3-AS1 data types