Across TCGA cell cohorts, DIABLO protein abundance is significantly associated with the RNA expression of many other genes, with 4,434 significant associations in total. BREAST shows the largest number of these associations.

The most reproducible DIABLO-associated genes across cancer lineages are VPS33A, PRKAB1, and BRI3BP. Each is linked with DIABLO in more than 9 cancer types. Because this analysis shows association rather than direction, both DIABLO-to-partner and partner-to-DIABLO results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DIABLO→partner) and Y-score (partner→DIABLO) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	VPS33A →	+0.838	+0.982	.004	<.001	3	10
BREAST	PRKAB1 →	+0.768	+0.976	<.001	<.001	3	9
BREAST	BRI3BP →	+1.012	+0.700	.001	.006	3	7
LUNG_NSCLC_LUAD	ZNF620 →	+0.960	+0.641	<.001	<.001	3	6
LUNG_SCLC	ZNF664 →	+0.990	+0.927	<.001	<.001	3	6
LUNG_NSCLC_LUAD	C12orf73 →	+0.649	+0.572	.001	.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,434 associations by consensus.

Exploration

DIABLO survival (RNA) · tumor vs normal (RNA) · all DIABLO data types