Across TCGA cell cohorts, DIABLO protein abundance is significantly associated with the go_rna of many other GO terms, with 2,219 significant associations in total. BREAST shows the largest number of these associations.

The most reproducible DIABLO-associated GO terms across cancer lineages are Mitochondrial transport, Dendritic transport of messenger ribonucleoprotein complex, and Regulation of establishment of T cell polarity. Each is linked with DIABLO in more than 4 cancer types. Because this analysis shows association rather than direction, both DIABLO-to-partner and partner-to-DIABLO results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (DIABLO→partner) and Y-score (partner→DIABLO) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Mitochondrial transport →	+0.113	+0.706	<.001	<.001	3	5
BONE	Dendritic transport of messenger ribonucleoprotein complex →	+0.079	+0.820	.003	.004	3	5
LARGE_INTESTINE	Regulation of establishment of T cell polarity →	-0.140	-0.450	<.001	.001	3	5
LUNG_SCLC	Negative regulation of lymphocyte mediated immunity →	-0.167	-0.945	<.001	<.001	3	5
LUNG_NSCLC_LUAD	Regulation of clathrin coat assembly →	+0.185	+0.582	<.001	<.001	3	5
LUNG_SCLC	Negative regulation of leukocyte mediated immunity →	-0.197	-1.005	<.001	.004	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,219 associations by consensus.

Exploration

DIABLO survival (RNA) · tumor vs normal (RNA) · all DIABLO data types