DHX58

RNA expression — cross-omics
Cross-omicsRNA → PROTEIN-MSPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, DHX58 RNA expression is significantly associated with the protein abundance of many other proteins, with 9,986 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible DHX58-associated proteins across cancer lineages are TRIM21, UBE2L6, and MX2. Each is linked with DHX58 in more than 9 cancer types. Because this analysis shows association rather than direction, both DHX58-to-partner and partner-to-DHX58 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, DHX58 versus TRIM21 in HNSC, with a Pearson correlation of 0.38.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (DHX58→partner) and Y-score (partner→DHX58) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner proteinX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
HNSCTRIM21 →+0.727+0.924<.001<.001310
LSCCUBE2L6 →+0.609+0.730<.001<.00139
HNSCMX2 →+0.765+0.739<.001<.00139
LSCCOAS2 →+0.853+0.703<.001<.00139
OVOAS3 →+0.820+0.983<.001<.00139
HNSCPARP14 →+0.544+0.903<.001<.00139
Each partner links to its Q-omics profile. Showing the 6 strongest of 9,986 associations by consensus.

DHX58 vs TRIM21 — HNSC

Per-sample scatter of DHX58 vs TRIM21 in HNSC (Pearson r = 0.38).

Explore this scatter interactively →

Exploration