DHX58

Across TCGA patient cohorts, DHX58 protein abundance is significantly associated with the RNA expression of many other genes, with 13,221 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible DHX58-associated genes across cancer lineages are OAS1, ETV7, and IFIT3. Each is linked with DHX58 in more than 8 cancer types. Because this analysis shows association rather than direction, both DHX58-to-partner and partner-to-DHX58 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, DHX58 versus OAS1 in BRCA, with a Pearson correlation of 0.69.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DHX58→partner) and Y-score (partner→DHX58) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	OAS1 →	+1.393	+0.543	<.001	<.001	3	9
BRCA	ETV7 →	+1.093	+0.347	.002	.004	3	8
HNSC	IFIT3 →	+1.572	+0.644	<.001	<.001	3	8
HNSC	RSAD2 →	+1.445	+0.604	<.001	<.001	3	8
HNSC	CMPK2 →	+1.255	+0.586	<.001	<.001	3	8
HNSC	OASL →	+1.518	+0.543	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,221 associations by consensus.

DHX58 vs OAS1 — BRCA

Explore this scatter interactively →