DHX58

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → PROTEIN-MSPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, DHX58 protein abundance is significantly associated with the protein abundance of many other proteins, with 23,679 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible DHX58-associated proteins across cancer lineages are IFIT1, DDX58, and CMPK2. Each is linked with DHX58 in more than 9 cancer types. Because this analysis shows association rather than direction, both DHX58-to-partner and partner-to-DHX58 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, DHX58 versus IFIT1 in HNSC, with a Pearson correlation of 0.75.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (DHX58→partner) and Y-score (partner→DHX58) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner proteinX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
HNSCIFIT1 →+1.125+0.680<.001<.001310
HNSCDDX58 →+0.818+0.665<.001<.00139
HNSCCMPK2 →+0.907+0.683<.001<.00139
HNSCSTAT1 →+0.604+0.519<.001<.00139
HNSCTRIM21 →+0.598+0.542<.001<.00139
HNSCIFIT2 →+1.194+0.631<.001<.00139
Each partner links to its Q-omics profile. Showing the 6 strongest of 23,679 associations by consensus.

DHX58 vs IFIT1 — HNSC

Per-sample scatter of DHX58 vs IFIT1 in HNSC (Pearson r = 0.75).

Explore this scatter interactively →

Exploration