DHX57

Across TCGA patient cohorts, DHX57 RNA expression is significantly associated with the protein abundance of many other proteins, with 20,544 significant associations in total. GBM shows the largest number of these associations.

The most reproducible DHX57-associated proteins across cancer lineages are PPM1G, SNRPD2, and SPAST. Each is linked with DHX57 in more than 5 cancer types. Because this analysis shows association rather than direction, both DHX57-to-partner and partner-to-DHX57 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, DHX57 versus PPM1G in GBM, with a Pearson correlation of 0.46.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (DHX57→partner) and Y-score (partner→DHX57) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	PPM1G →	+0.345	+0.296	<.001	<.001	3	6
GBM	SNRPD2 →	+0.331	+0.393	<.001	<.001	3	6
LSCC	SPAST →	+0.366	+0.418	<.001	<.001	3	6
LSCC	FXR1 →	+0.427	+0.621	<.001	<.001	3	6
HNSC	HNRNPLL →	+0.356	+0.728	<.001	<.001	3	6
LSCC	MSH2 →	+0.485	+0.607	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 20,544 associations by consensus.

DHX57 vs PPM1G — GBM

Explore this scatter interactively →