DHX57

Across TCGA patient cohorts, DHX57 protein abundance is significantly associated with the RNA expression of many other genes, with 15,313 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible DHX57-associated genes across cancer lineages are WDCP, CENPO, and GTF3C2. Each is linked with DHX57 in more than 6 cancer types. Because this analysis shows association rather than direction, both DHX57-to-partner and partner-to-DHX57 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, DHX57 versus WDCP in LSCC, with a Pearson correlation of 0.68.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DHX57→partner) and Y-score (partner→DHX57) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	WDCP →	+0.654	+0.350	<.001	<.001	3	7
BRCA	CENPO →	+0.720	+0.313	<.001	<.001	3	7
LSCC	GTF3C2 →	+0.362	+0.309	<.001	<.001	3	6
LSCC	NOL10 →	+0.530	+0.332	<.001	<.001	3	6
LSCC	CPSF3 →	+0.485	+0.335	<.001	<.001	3	6
BRCA	SLC5A6 →	+1.154	+0.341	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,313 associations by consensus.

DHX57 vs WDCP — LSCC

Explore this scatter interactively →