DHX40

Across TCGA patient cohorts, DHX40 RNA expression is significantly associated with the protein abundance of many other proteins, with 16,772 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible DHX40-associated proteins across cancer lineages are BPTF, COIL, and LUC7L3. Each is linked with DHX40 in more than 7 cancer types. Because this analysis shows association rather than direction, both DHX40-to-partner and partner-to-DHX40 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, DHX40 versus BPTF in LSCC, with a Pearson correlation of 0.64.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (DHX40→partner) and Y-score (partner→DHX40) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	BPTF →	+0.291	+0.703	<.001	<.001	3	8
LSCC	COIL →	+0.481	+0.662	<.001	<.001	3	7
GBM	LUC7L3 →	+0.306	+0.365	<.001	.003	3	6
GBM	BCLAF1 →	+0.360	+0.384	<.001	<.001	3	6
LSCC	DHX8 →	+0.390	+0.814	<.001	<.001	3	6
HNSC	NIPBL →	+0.303	+1.019	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 16,772 associations by consensus.

DHX40 vs BPTF — LSCC

Explore this scatter interactively →